Urinary concentrating ability in early experimental pyelonephritis
نویسندگان
چکیده
منابع مشابه
Urinary concentrating ability in early experimental pyelonephritis.
The effect of early bilateral pyelonephritis on urinary concentrating ability was studied in rats injected intravenously with enterococci or Staphylococcus aureus and in rats inoculated with Escherichia coli into the medullae of both kidneys. The mean maximum urinary osmolality of normal rats was 2352 mOsm/kg of water. Inoculation of E. coli caused reversible pyelonephritis with sterilization o...
متن کاملEffect of Experimental Pyelonephritis on the Renal Concentrating Ability of the Rat §
The intravenous injection of virulent staphylococci produces renal infection in 75 to 100 per cent of normal rats.' The renal lesion persists for many months and carries with it little mortality. This model is suitable for the study of disturbances of renal function due to infection, since prior ureteral obstruction or localized renal damage is not required. The present experiments were underta...
متن کاملImpaired urinary concentrating ability in genetically polyuric mice.
Newly recognized strain of mice with hereditary polyuria (PUS mice) was characterized. Polyuria was inherited as a single autosomal-recessive trait. At 15 weeks, PUS mice excreted hypotonic (urine osmolality: PUS;270.8 +/- 15.5 vs. cont.; 3,228.6 +/- 163.6 mosm/kg) polyuria (urine volume: PUS; 25.0 +/- 1.5 vs. cont.; 1.1 +/- 0.1 ml/day). In PUS mice, plasma osmolality was slightly elevated as w...
متن کاملContribution of urea to urinary concentrating ability in the dog.
SCHMIDT-NIELSEN, BODIL, AND ROSCOE R. ROBINSON. Contribution of urea to urinary concentrating ability in the dog. Am. J. Physiol. 218(5): 1363-1369. 1970.-Dogs were maintained on balanced highand low-protein diets for 3 weeks prior to the experiments. Urea clearance, inulin clearance, and solute concentrations in the various zones of the kidney were determined. The glomerular filtration rates a...
متن کاملThe critical importance of urinary concentrating ability in the generation of urinary carbon dioxide tension.
Measurement of urine to blood (U-B) carbon dioxide tension (P(CO2)) gradient during alkalinization of the urine has been suggested to assess distal H(+) secretion. A fact that has not been considered in previous studies dealing with urinary P(CO2) is that dissolution of HCO(3) in water results in elevation of P(CO2) which is directly proportional to the HCO(3) concentration. To investigate the ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1970
ISSN: 0021-9738
DOI: 10.1172/jci106360